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Fisetin 98%

Fisetin 98%

【English name】Fisetin
【English alias】C.I. 75620; C.I. Natural Brown 1; Fisetin; 3,3,4,7-Tetrahydroxyflavone; 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4-one
【Molecular formula】 C15H10O6
【Molecular weight】 286.23
【CAS No.】528-48-3

Description

Product Introduction

Fisetin powder is a kind of flavonol, hardly soluble in water, carbon tetrachloride and petroleum ether, easily soluble in solvents such as acetone, acetic acid, etc. It is widely present in fruits and vegetables such as strawberries, apples, onions, cucumbers, and has a wide range of sources , Cheap and easy to obtain, has a wide range of pharmacological activities, such as anti-inflammatory, anti-oxidation, anti-coagulation, anti-thrombosis, antispasmodic, treatment of diabetic kidney injury, etc.

In recent years, studies have found that lacustrine can play an anti-tumor effect by inhibiting tumor cell proliferation and signal transduction pathways, and inducing tumor cell apoptosis. Therefore, it has received increasing attention. However, this ingredient has shortcomings such as insoluble in water and low bioavailability, which limits its further development and clinical application. At present, the research on fischerin mainly focuses on pharmacological activity, mechanism of action, extraction process, etc. There are few reports on related dosage forms.


English name:Fisetin 98%

English alias:C.I. 75620; C.I. Natural Brown 1; Fisetin; 3,3,4,7-Tetrahydroxyflavone; 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4-one

Molecular formula: C15H10O6

Molecular weight: 286.23

CAS No.:528-48-3

Detection method:High performance liquid chromatography HPLC≥98%

Specification:10mg 20mg 100mg 500mg 1g (can be packaged according to customer needs)

Appearance:yellow needle crystal

Source of extraction:Rhus succedanea L


Product Name

Fisetin

Batch number

WSF220310

Botanical Name

Cotinus coggygria

Country of origin:

China

Part Used

Herb

Manufacture date

2022-03-10

Batch quantity

50kg

Expiration Date

2024-03-09

Analysis

Specification

Results

Method

Assay(Fisetin)

≥98.0%

98.62%

HPLC-AREA

Assay(Fisetin)

≥85.0%

85.1%

HPLC

Appearance

Yellow Powder

Complies

Visual

Odor

Characteristic

Complies

Organoleptic

Taste

Characteristic

Complies

Organoleptic

Loss on drying

≤5.0%

4.25%

CP2015

Total Ash

≤5.0%

0.47%

CP2015

Heavy Metals:




Total

≤10ppm

Complies

CP2015

As

≤2ppm

Complies

CP2015

Pb

≤2ppm

Complies

CP2015

Cd

≤1ppm

Complies

CP2015

Hg

≤0.1ppm

Complies

CP2015

Microbiological Control




Total Plate Count

NMT1000cfu/g

Complies

CP2015

Yeast & Mold

NMT100cfu/g

Complies

CP2015

E.Coli

Negative

Complies

CP2015


Packing and Storage


Packing

25kgs/drum. Packing in paper-drums and two plastic-bags inside.

Storage

Store in cool & dry place,Keep away from strong light and heat

Shelf Life

2 years.


Production function

Fisetin powder has anti-oxidant, anti-inflammatory and neuroprotective pharmacological characteristics. It can play a role in inducing tumor cell apoptosis, influencing tumor cell signal transduction pathways, inhibiting tumor cell proliferation, and inhibiting tumor cell migration and invasion. Anti-tumor effect;

Studies have shown that iochlavin can also exert an antidepressant effect by inhibiting the monoamine oxidase of the serotonin and norepinephrine system; it has obvious protective and repair effects on liver damage caused by hepatitis; it can significantly improve the activity of immune cells.

Physical character: yellow needle-like crystals, melting point 3300C (decomposition). Soluble in ethanol, acetone and acetic acid. Almost insoluble in water, ether, benzene, chloroform and petroleum ether.





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