What is Camptotheca acuminata extract?
Camptotheca acuminata extract is of rich Camptothecin (CPT), a cytotoxic quinoline alkaloid, can inhibit DNA topoisomerase (TOPO I). Anticancer drugs were discovered in 1966 by M.E. Wall and M.C. Wani through systematic screening of natural substances.
Camptothecin is isolated from the bark and branches of the Camptothecus tree (Camtothecus japonica, the tree of happiness) produced in China, and was used in the early days of traditional Chinese medicine to treat cancer. Camptothecin has significant anticancer properties in preliminary clinical trials, has low solubility, and contains a high degree of adverse drug reaction profile. Medicinal chemists have in turn exploited these properties to develop a variety of synthetic camptothecins and various derivatives for added benefit. There are now two analogs of camptothecin approved and used for cancer chemotherapy, such as topotecan and irinotecan.
Latin name: Camptotheca acuminata
Part used: Fruit or leaf
Specification: 95%, 98% Camptothecin
Appearance: Light Yellow Needle-like Crystal
Camptotheca acuminata extract is a semi-finished raw material and serves only corporate customers with processing capabilities instead of to individual consumers. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem.