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Ginkgo Biloba Extract

Ginkgo Biloba Extract

24% Total Ginkgo flavone Glycosides, 6% Total Terpene Lactone, NMT 5ppm biloba acid.

Description

Ginkgo Biloba Extract

Ginkgo biloba extract, GBE in short is the most successful application of phytomedicine. Standardrized specication is 24% Total Ginkgo flavone Glycosides, 6% Total Terpene Lactone. It is a popluare medicine for cardiovacular medicine.


Below is typical method to produce ginkgo biloba extract.

Remove foreign matter and and mold leaves, wash and dry.reflux with 70% ethanol and , extract the solution, filter, recover the ethanol under reduced pressure, centrifuge at high speed to remove the residue, dilute with an appropriate amount of pure water, and add to the macroporous adsorption resin column. Wash with column until the eluent is clear and light in color. Then elute with a proper volume ethanol, collect the eluent, concentrate under reduced pressure, and dry under vacuum.


ginko bilobaginko biloba extract
Ginkgo Biloba leafGinkgo Biloba Extract


Product Specification

English name:

Ginkgo Biloba Extract

Latin name:

Folium Ginkgo

Active ingredients:

Ginkgo flavone Glycosides/Terpene Lactone

Part used:

leaf

Appearance

Brown Yellow Powder

Odor:

Characteristic

Specification:

24% Total Ginkgo flavone Glycosides, 6% Total Terpene Lactone

Test Method:

HPLC


CERTIFICATE OF ANALYSIS

Product name: Ginkgo Biloba Extract CP2015/ USP41

Mfg.Date:Jun.2020

Batch No.:20200627

Exp.Date:Jun.2023

Quantity: 1000kg

General Information

Part Used:100% Leaves

Solvents Used:Water&Ethanol

Botanical Source :Ginkgo biloba L.

Country Of Origin:China

ITEMS

SPECIFICATION

METHOD

TEST RESULTS

Physical&Chemical Data




Identification

Corresponds to Reference Standard

Complies

HPTLC || USP<203>

Color

Yellow brown to brown fine powder

Organoleptic

Conform

Odour

Characteristic

Organoleptic

Conform

Appearance

Fine Powder

Organoleptic

Conform

Analytical Quality




Identification

SPECIFICATION

METHOD

TEST RESULTS

Total Ginkgo Flavonglycosides

≥24.0%

HPLC || CP2015

24.40%

Quercetin/Kaempferol

0.8~1.2

HPLC

1.03

Isorhamnet/ Quercetin

≥0.15

HPLC

0.27

Quercetin

/

HPLC

10.87%

Kaempferol

/

HPLC

10.60%

Isorhamnetin

/

HPLC

2.93%

Free Quercetin

≤10 mg/g

HPLC

1.7 mg/g

Free Kaempferol

≤10 mg/g

HPLC

0.6 mg/g

Free Isorhamnetin

≤ 4 mg/g

HPLC

0.4 mg/g

Total Terpene Lactones

≥6.0%

HPLC || CP2015

6.59%

Ginkgolides A

/

HPLC

1.79%

Ginkgolides B

/

HPLC

0.81%

Ginkgolides C

/

HPLC

1.10%

Bilobalides

/

HPLC

2.89%

Ginkgolic Acid

≤5ppm

HPLC || CP2015

1.05ppm

Sieve analysis

100% through 80 mesh

CP2015

Conform

Loss on drying

≤5.0 %

CP2015

3.03%

Bulk Density

40~60 g/100mL

CP2015

55g/100mL

Tap density

60~90g/100mL

CP2015

80g/100mL

Contaminants




Lead(Pb)

≤2.0 mg/kg

ICP-MS || USP<730>

0.11

Arsenic(As)

≤2.0 mg/kg

ICP-MS || USP<730>

0.17

Cadmium(Cd)

≤1.0 mg/kg

ICP-MS || USP<730>

ND

Mercury(Hg)

≤1.0 mg/kg

ICP-MS || USP<730>

ND

Solvents Residue

Meets Requirements

GC || USP<467>

Conform

Microbiological




Total Plate Count

≤1000 cfu/g

CP2015

37

Yeast &Mold

≤100 cfu/g

CP2015

22

E.Coli

≤10 cfu/g

CP2015

Conform

Staphylococcus aureus

≤10 cfu/g

CP2015

Conform

Salmonella

≤10 cfu/g

CP2015

Conform

Packing&Storage

Packed in paper-drums and two plastic-bags insid



N.W:25kgs .I.D.38×H45cm;




Store in a well-closed container Away from moisture,light, oxygen.

Shelf life

36 months under the conditions above and in its original packaging.


Function and Application :

1. Ginkgo biloba extract is mainly used in treating the bad memory and relaxing the mental anxiety. Ginkgo in Europe has been widely used to treat dementia.

2. Ginkgo is thought to help prevent these brain disorders because of its antioxidant
3. The extract from ginkgo biloba also has the great effect on high blood pressure, asthma and bronchitis.

4. It can protect our cardiovascular and promote the blood circulation
Application:
a. The raw plant can be used as the animal feed.
b. The extract has been used in the capsule, tablets and ointment.

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