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Shikimic Acid powder

Shikimic Acid powder

Product Name: star anise extract
Latin name: Illicium verum Hook.f.
Part used:dry fruit
Specification: 10%-98% shikimic acid Appearance: brown to white fine powder

Description

Product Introduction

Shikimic acid powder is an organic compound with a molecular formula of C7H10O5. It is colorless or white needle-like crystals. The solubility in water at 20°C is 18%, slightly soluble in ethanol and ether, and almost insoluble in chloroform and benzene. By affecting the metabolism of arachidonic acid, shikimic acid inhibits platelet aggregation, inhibits the formation of arterial and venous thrombosis and cerebral thrombosis, and has anti-inflammatory and analgesic effects. It can also be used as an anti-viral and anti-cancer drug intermediate. This product is mostly used as a pharmaceutical intermediate, which is irritating and should not be used directly .

Product Character

Product Name: star anise extract

Latin name: Illicium verum Hook.f.

Part used:dry fruit

Specification: 10:1

Appearance: 10%-98% shikimic acid


Tamiflu's key ingredient shikimic acid. The shikimic acid currently used by Roche is processed and extracted from star anise.

The process of synthesizing shikimic acid from petrochemical raw materials is complicated, and there is no production and application value except for scientific research.


Pharmacological effects Shikimic acid powder has anti-inflammatory and analgesic effects by affecting the metabolism of arachidonic acid, inhibiting platelet aggregation, and inhibiting the formation of arterial and venous thrombosis and cerebral thrombosis. It also has anti-inflammatory and analgesic effects. It can also be used as an anti-viral and anti-cancer drug intermediate, as well as preventive The effects of the bird flu drugs "Tamiflu" and "Keflu". Shikimic acid pathway The shikimic acid pathway is an important metabolic pathway that exists in plants, fungi and microorganisms.


Shikimic acid powder is used as the starting material of oseltamivir (the active ingredient of Tamiflu), which is a neuraminidase inhibitor and can be used to treat and prevent influenza A and influenza B.

Physical Characteristics



Particle Size

100% Through 80 mesh

Conforms

Loss on Drying

≤5%


ash

≤5%


Heavy metals



Methanol

≤ 3000mg/kg

Conforms

acetone

≤ 5000mg/kg

Conforms

n-hexane

≤ 290mg/kg

Conforms

Density



loose density

≥ 0.30g/mL

Conforms

tight density

≥ 0.50g/mL

Conforms

Microbiological Tests



Total Plate Count

≤3000cfu/g

Conforms

Total Yeast & Mold

≤300cfu/g

Conforms

E.Coli

Negative

Negative

Salmonella

Negative

Negative

Staphylococcus

Negative

Negative

Storage: Preserve in well-closed, light-resistant, and protect from moisture.




Toxicity

acute toxicity, abdominal cavity-mouse LD50: 600 mg/kg

The warehouse is low temperature, ventilated and dry.






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