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botanical extract as antibiotic alternatives

Jun 18, 2021

Vententary antibotics

The fundamental transformation of animal husbandry production from "quantitative change" to "qualitative change" is also required. Products produced by animal husbandry will eventually be on people’s tables. Food safety has become a national strategy. How to eat well and safely has become a new goal, so whoever leads the food terminal will lead the future of animal husbandry production.

Whether it is the increasing demands of consumers for food safety or the country’s gradual strictness against “anti-resistance”, non-resistance is the general trend. Antibiotic alternatives have become the direction of research and development of many biotech companies, among which the effect of plant extracts on pig production obvious.

Anti-antibiotic & animal

Antibiotic alternatives

In last 30 years of animal husbandry production, antibiotics contributes indispensable. However, with the tremendous and irregular use of antibiotics, drug-resistant bacteria and mutant strains emerge constantly. The antibiotics abuse has become a new obstacle to animal husbandry production, regardless of whether the animal husbandry producers wish it or not. Reducing or substituting or even eliminating resistance has become a new trend, which commence the post-antibiotic era arrival.

Anti-resistance feed is a systematic project, which that requires many aspects such as breeding, management, nutrition, prevention, and biosafety. This article only lists the relevant parts of feed production and breeding for exchange.

Anti-antibiotic feed is very easy to achieve, and veterinary antibiotics should not be added to feed originally. Feed is the part that provides nutrition, it should not bear the role of disease resistance, and the rational use of antibiotics in the breeding process is okay

antibiotic alternatives

Natural extract as antibotic alternative

Anti-bacteria products can be divided into two categories:

One is effective antibiotic alternatives, including enzyme preparations, microecological agents, acidifiers and zinc oxide, etc., which are mainly regulated from two aspects of nutrient digestion and absorption to reduce disease and reduce the use of antibiotics. ;

The second is functional replacement products, such as traditional Chinese herbal medicines, plant essential oils, plant extracts, which have the same sterilization mechanism as antibiotics, and the clinical treatment effect is definite.

Active component in plant extracts

Plant extracts are derived from natural plant, through physical or chemical methods, the active components are extracted directionally, but their chemical structure is not changed. Plant extracts can be divided into acids, aldehydes, polyphenols, saponins, polysaccharides, Reducing sugar , flavonoids, alkaloids and terpenes according to the extracted components.

The commone product appereance can be divided into plant essential oils, plant powders, lenses and extracts, which are used in animal husbandry production. There are more extracts with low cost and stable benefit. In terms of production process, water extraction, ester extraction, alcohol extraction, and microwave extraction are popular. While the devided components include polysaccharides, chlorogenic acids, flavonoids, polyphenols, oligosaccharides.

Below will show brief introduction.

*The natural immune inducer of plant polysaccharides induces the body to produce interferon, which can simultaneously compete with the virus for receptors on the surface of target cells, block the virus from occupying positions, stimulate the growth of intestinal crypts, promote the secretion of B and T cells, and improve cellular immunity. It is clinically used and antiviral. At the same time, some polysaccharides also have bactericidal effects. We are mostly used for the prevention and treatment of viral diseases.

chlorogenic acid

*chlorogenic acid is a natural bactericidal substance. It is found in large quantities in honeysuckle plants. It has obvious effects on Escherichia coli, Typhoid bacillus, Pseudomonas aeruginosa, Staphylococcus aureus, Clostridium and pneumococcus, etc. It also has a significant effect on lactic acid bacteria. , Bifidobacterium has a selective proliferation effect, and we are often clinically used for the treatment of diarrhea, respiratory tract infection, exudative dermatitis, and tissue infection.

Botanical flavonoids

*Botanical flavonoids are similar in structure to progesterone in animals. They have mild estrogen effects. They are effective in reproduction of sows, cows, and laying hens. At the same time, It encourage protein assimilation and promote growth. Secondly, some flavonoids have antioxidant properties. To eliminate toxins, soy isoflavones and pueraria flavonoids are commonly used to breed female animals, which have obvious effects on female animals' return to estrus, breeding, and lactation, and have an effect on fattening pigs and broiler chickens in the later stages of weight gain.


Plant polyphenols are natural antioxidants, which have a significant effect on fat metabolism. They can promote the decomposition of fats, improve the utilization of fats by animals, are beneficial to promote growth, protect the liver and gallbladder, and prevent disease, stress, and nutritional metabolism. The toxins are excreted from the body through the binding of glucuronic acid, reducing the occurrence of liver-derived diseases. In aquaculture production, it is often used to decompose fat to increase energy, as a natural antioxidant, as a liver and gallbladder protection drug, and as an anti-stress drug.

Reducing sugar

Reducing sugar is a collective term for monosaccharides and oligosaccharides, which can increase energy, and has a significant effect on the reproduction of lactic acid bacteria and bifidobacteria, promote immunity, improve the intestinal environment, and promote digestion and absorption. In practice, the constipation and lack of milk in sows have been significantly improved, and the antibody titer of the vaccine has been significantly improved.

There are many sources of plant extracts. Chinese herbal medicine is only a part of the plant. The use cost is relatively high. The plant extract can be used as medicine. At the same time, it can be extracted from non-"pharmacopoeia" plants, so that the cost is low, and the extraction is carried out according to a certain ratio. The common ratio is 1:4~1: 25. The extracted substance is equivalent to 4 to 25 times of the original drug, which can reduce the amount of addition.

During the breeding process, we can completely replace antibiotics for daily health care, on the one hand, reducing costs, on the other hand, preventing drug resistance. In that case, increased antibiotics dosage can be used for treatment. Since each antibiotics may result resistance after long term application, a single plant extract cannot be an ideal result. To solve the problem, extract complex is a good choice. Extract formula can is designed after experiment and trials to determine the final ingredient to ensure effect and reduce harm.

Benefit of Natural extract in feed

Large amount of research data has shown that plant extracts have positive functions in animal health. It is as follows.

1) Good food attraction effect, and the extracted aromatic substances can effectively improve palatability and increase feed intake;

2) Good bactericidal effect, chlorogenic acid is a natural bactericidal substance and is obvious to promote growth.

3) The reproduction of female animals is promoted;

5 ) Outstanding anti-stress effect;

6) Promote the absorption of feed inorganic salt.