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Super Antioxidant Astaxanthin

Nov 20, 2020


Astaxanthin is a keto carotenoid with the chemical name 3,3'-dihydroxy-4,4'-diketo-β,β'-carotene, a red solid powder, fat-soluble, insoluble Water, soluble in organic solvents. [1]  . It is widely found in the biological world, especially in the feathers of aquatic animals such as shrimps, crabs, fish and birds. It plays a role in color development.

 

Astaxanthin is a chain-scission antioxidant. It has strong antioxidant capacity, can remove nitrogen dioxide, sulfide, disulfide, etc., can also reduce lipid peroxidation, and effectively inhibit lipid peroxidation caused by free radicals. At the same time, it has various physiological effects such as inhibiting tumor occurrence, enhancing immunity, removing free radicals in the body, etc., has a good therapeutic effect on skin cancer caused by ultraviolet rays, and has a preventive effect on eye diseases caused by diabetes. It is used in health care products.

In addition to being obtained by biological extraction, astaxanthin can also be produced from chemical synthesis, or by algae, bacteria, yeast, etc.

 

Haematococcus pluvialis cultivation                        Astaxanthin and gel

 

*Anticancer

The investigation of the relationship between dietary carotenoid intake and cancer incidence or mortality showed that the total cancer incidence or mortality was significantly negatively correlated with carotenoid intake. Comparing the anti-tumor activities of various carotenoids, astaxanthin has the strongest effect. The anti-tumor activity of astaxanthin may be related to its signal transduction between cells, the induction of metabolizing enzymes for heterogeneous substances, and the regulation of immune responses related to tumor cells.

 Studies have shown that astaxanthin can inhibit the mutagenic effects of aflatoxin B1, phenylpropionyl pyrene (BaP), diethyl nitrous acid (DEN), nitrosamines and cyclophosphamide, etc.

Astaxanthin can prevent tumors. It plays a role in different stages of tumor formation. For example by inhibiting the production of putrescine and reducing the free polyamines such as spermine and spermidine, reducing tumor-inducing substances; protecting the skin from UV damage through antioxidant effects, preventing skin By strengthening the connection ability between normal cells, the cells induced by carcinogens are placed in an expanded communication network, so that the normal cells are dominant, isolated cancer cells, reducing the connection between cancer cells, controlling their growth, and preventing tumor transformation ;

astaxanthin also has a strong inhibitory effect on cancer cell proliferation, and high concentration of astaxanthin can kill tumor cells. Studies have found that astaxanthin can effectively control a variety of cancers, such as liver cancer, oral cancer, colorectal cancer, bladder cancer and breast cancer.