Alcohol Abuse Situation
Alcohol culture has a history of more than a thousand years, because social drinking can help close social relationships, and at the same time, the harm caused by alcohol dependence and drunkenness has brought a lot of trouble to society and individuals.
According to the World Health Organization, about 3 million people die from alcoholism every year. In order to solve this problem, people have conducted extensive research to find a way to suppress drinking habits, or at least reduce drinking. Dihydromyricetin (DHM) deserves attention in this field. It can treat alcoholism, drunkenness syndrome, solve sobering problems and so on.
To understand how dihydromyricetin achieves a hangover, we need to understand why people get hangovers.
Hangover is the experience of various uncomfortable physical and psychological sensations/symptoms after drinking alcohol. A hangover can last for several hours or more than a day. Typical symptoms of a hangover may include headache, dry mouth, dizziness, inability to concentrate, fatigue, gastrointestinal distress (such as vomiting), lack of hunger, sweating, nausea, hyperexcitability, anxiety, and sleep problems.
Alcohol (the chemical name is ethanol) enters the stomach and liver through the mouth after drinking. In fact, alcohol itself is not harmful to the liver, and the substances produced when the liver breaks down alcohol may cause damage to the organs. Acetaldehyde is a contributing factor.
After ethanol enters the human body, part of it will be eliminated from the body through breathing and sweat, and most of it will enter the liver for metabolism. After ethanol enters the liver, it will generate acetaldehyde under the action of alcohol dehydrogenase. Acetaldehyde is harmful to the human body. Acetic acid is produced under the action of aldehyde dehydrogenase, so the liver is also called the hangover organ.
Feeling happy after drinking, dizziness, floating sensation, red face and neck, becoming talkative or speechless... all because of the effect of alcohol on the brain. Someone will start to come to the toilet because the liver is working to release enzymes that break down alcohol. However, when a person drinks excessively, it will cause a large amount of alcohol to accumulate in the liver. The liver secretes a limited amount of alcohol dehydrogenase that cannot process so much ethanol, so it will cause ethanol to accumulate in the liver and brain, leading to alcoholism.
There are usually two enzymes in the human body-alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH2). The former converts the ethanol (alcohol) that enters the body into acetaldehyde, and the latter converts acetaldehyde into acetic acid. , The final acetic acid is excreted from the body, and the metabolic process of alcohol is over.
How alcohol break down in liver?
Under normal circumstances, the two enzymes work normally. As long as you don't consume too much alcohol, acetaldehyde will quickly be converted into acetic acid.
The liver metabolizes alcohol through the following three steps:
1. Under the action of alcohol dehydrogenase, alcohol is converted into acetaldehyde; a highly toxic substance known to cause hangover symptoms.
2. Acetaldehyde is converted into acetic acid under the action of acetaldehyde dehydrogenase;
3. Finally, acetic acid is decomposed into carbon dioxide and water, which are excreted from the body.
How does dihydromyricetin relieve hangover？
Teng tea dihydromyricetin is a wild woody vine plant belonging to the genus Snake grapes in the grape family. The main active ingredient is flavonoids. This type of substance has many functions such as scavenging free radicals, anti-oxidation, anti-thrombosis, anti-tumor, anti-inflammatory, etc. A peculiar effect; and dihydromyricetin is a special kind of flavonoids. In addition to the general characteristics of flavonoids, it also has the ability to relieve alcoholism, prevent alcoholic liver, fatty liver, inhibit liver cell deterioration, and reduce liver cancer. Incidence and other effects. It is a good product to protect the liver and liver, hangover and sober up.
1. Dihydromyricetin can improve the increase of serum lactate dehydrogenase activity caused by liver cell damage, dihydromyricetin accelerates the decomposition of alcohol, dihydromyricetin can protect the liver, accelerate the rapid decomposition of ethanol metabolite acetaldehyde, and become non-toxic Substance, reduce damage to liver cells. Dihydromyricetin has a rapid onset and long-lasting effect. It is a good product for protecting the liver, protecting the liver, and sobering up alcohol.
2. Dihydromyricetin (DHM)-has a special ability to prevent drunkenness. Its magic is that no matter how high the alcohol content in the blood is, it can prevent the brain from feeling the intoxicating effects. DHM can indeed increase the speed of a person's wakefulness after drinking. It happens in two ways:
*Reduce the impact of alcohol on the brain
Most of the common symptoms of alcoholism, such as decreased inhibition, slurred speech, and loss of balance, are caused by the action of GABA receptors in the brain. Even if the blood alcohol content is still high, dihydromyricetin has the ability to counteract this effect.
*Improve liver function
The liver needs enough time to completely process the alcohol and expel it from the system. With the help of DHM, the liver can work faster and the patient can wake up faster.